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Article

Relationship between homologous recombination deficiency and clinical features of breast cancer based on genomic scar score.

Breast (Edinburgh, Scotland) - 1 Jun 2023

Feng Cong, Zhang Yinbin, Wu Fei, Li Jia, Liu Mengjie, Lv Wei, Li Chaofan, Wang Weiwei, Tan Qinghua, Xue Xiaoyu, Ma Xingcong, Zhang Shuqun

Abstract excerpt

BACKGROUND: Homologous recombination deficiency (HRD) phenotype will sensitize tumors to poly (ADP-ribose) polymerases inhibitors and platinum. However, previous studies did not focus on the prevalence of HRD among Chinese breast cancer (BC) patients. METHODS: One hundred and forty-seven BC patients were included in this study. Their HRD status was assessed by Genomic Scar Score (GSS), which was determined...

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Identifiers

PMID: 37116400
DOI: 10.1016/j.breast.2023.04.002
PMCID: PMC10165146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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