Article
Haplotypes spanning centromeric regions reveal persistence of large blocks of archaic DNA
2018-06-20
Abstract excerpt
Despite critical roles in chromosome segregation and disease, the repetitive structure and vast size of centromeres and their surrounding heterochromatic regions impede studies of genomic variation. We report here large-scale haplotypes ( cenhaps ) in humans that span the centromere-proximal regions of all metacentric chromosomes, including the arrays of highly repeated α-satellites on which centromeres form. Ce...
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Identifiers and source
- Literature Corpus work
- 28422a3d-0edd-52c4-a85b-d5e28d7a8fb0
- DOI
- 10.1101/351569