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Article

Long-read Data Revealed Structural Diversity in Human Centromere Sequences

2019-09-27

Abstract excerpt

<h4>ABSTRACT</h4> Centromeres invariably serve as the loci of kinetochore assembly in all eukaryotic cells, but their underlying DNA sequences evolve rapidly. Human centromeres are characterized by their extremely repetitive structures, i.e. , higher-order repeats, rendering the region one of the most difficult parts of the genome to assess. Consequently, our understanding of centromere sequence variations acros...

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Literature Corpus work
35f18eb7-229a-5d94-89ac-27db4462c064
DOI
10.1101/784785
Open publication

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Long-read Data Revealed Structural Diversity in Human Centromere SequencesDOI 10.1101/784785
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