Article
A whole-organism landscape of X-inactivation in humans
2023-06-27
Abstract excerpt
As females are mosaic for X-inactivation, direct determination of X-linked allelic expression in bulk tissues is typically unfeasible. Using females that are non-mosaic (completely skewed) for X-inactivation (nmXCI) has proven a powerful and natural genetic system for profiling X-inactivation in humans. By combining allele-resolution data for one previously reported and two newly identified nmXCI females, we direc...
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Identifiers and source
- Literature Corpus work
- cc94ce34-0e4a-57df-892d-25838381717f
- DOI
- 10.1101/2023.06.26.546519