Article

Induction of Dopaminergic Neurons for Neuronal Subtype-Specific Modeling of Psychiatric Disease Risk

2021-04-02

Abstract excerpt

<h4>ABSTRACT</h4> Dopaminergic neurons are critical to movement, mood, addiction, and stress. Current techniques for generating dopaminergic neurons from human induced pluripotent stem cells (hiPSCs) yield heterogenous cell populations with variable purity and inconsistent reproducibility between donors, hiPSC clones, and experiments. Here, we report the rapid (5 weeks) and efficient (~90%) induction of induced d...

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Literature Corpus work: cc404a72-b01b-5bbd-8e46-fc78204c8616
DOI: 10.1101/2021.04.01.438094

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