Article

Single cell transcriptional and functional analysis of human dopamine neurons in 3D fetal ventral midbrain organoid like cultures

2020-10-01

Abstract excerpt

<h4>SUMMARY</h4> Transplantation of midbrain dopamine (DA) neurons for the treatment of Parkinson’s disease (PD) is a strategy that has being extensively explored and clinical trials using fetal and stem cell-derived DA neurons are ongoing. An increased understanding of the mechanisms promoting the generation of distinct subtypes of midbrain DA during normal development will be essential for guiding future effort...

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Literature Corpus work: 4e0ada8b-3aab-5b33-927c-1d10085070a3
DOI: 10.1101/2020.10.01.322495

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