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Article

A Dishful of a Troubled Mind: Induced Pluripotent Stem Cells in Psychiatric Research

29 Dec 2015

Abstract excerpt

Neuronal differentiation of induced pluripotent stem cells and direct reprogramming represent powerful methods for modeling the development of neurons in vitro. Moreover, this approach is also a means for comparing various cellular phenotypes between cell lines originating from healthy and diseased individuals or isogenic cell lines engineered to differ at only one or a few genomic loci. Despite methodological...

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PMID: 26839567
DOI: 10.1155/2016/7909176

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