Article

Dual TCR-alpha expression on MAIT cells as a potential confounder of TCR interpretation

2021-03-26

Abstract excerpt

Mucosal-associated invariant T (MAIT) cells are innate-like T cells that are highly abundant in human blood and tissues. Most MAIT cells have an invariant T cell receptor (TCR) α chain that uses TRAV1-2 joined to TRAJ33/20/12 and recognize metabolites from bacterial riboflavin synthesis bound to the antigen-presenting molecule, MR1. Recently, our attempts to identify alternative MR1-presented antigens led to the d...

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Literature Corpus work: cc3f540a-9c7f-5308-977e-2e004bb92623
DOI: 10.1101/2021.03.25.436871

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