Article
Characterization of Human Mucosal-associated Invariant T (MAIT) Cells.
Current protocols in immunology - 1 Dec 2019
Souter Michael N T, Loh Liyen, Li Shihan, Meehan Bronwyn S, Gherardin Nicholas A, Godfrey Dale I, Rossjohn Jamie, Fairlie David P, Kedzierska Katherine, Pellicci Daniel G, Chen Zhenjun, Kjer-Nielsen Lars, Corbett Alexandra J, McCluskey James, Eckle Sidonia B G
Abstract excerpt
Mucosal-associated invariant T (MAIT) cells are a subset of unconventional T cells restricted by the major histocompatibility complex (MHC) class I-like molecule MHC-related protein 1 (MR1). MAIT cells are found throughout the body, especially in human blood and liver. Unlike conventional T cells, which are stimulated by peptide antigens presented by MHC molecules, MAIT cells recognize metabolite antigens derived...
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