Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis

5 Jun 2019

Abstract excerpt

Abstract Mucosal-associated invariant T (MAIT) cells typically express a TRAV1-2 + semi-invariant TCRα that enables recognition of bacterial, mycobacterial, and fungal riboflavin metabolites presented by MR1. MAIT cells are associated with immune control of bacterial and mycobacterial infections in murine models. Here, we report that a population of pro-inflammatory TRAV1-2 + CD8 + T cells are present in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31231693
DOI: 10.1038/s42003-019-0442-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosisPMID 31231693Read ↗

Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigensSemantic proximity Read ↗

Identification and Phenotype of MAIT Cells in Cattle and Their Response to Bacterial Infections.Semantic proximity Read ↗

Dual TCR-alpha expression on MAIT cells as a potential confounder of TCR interpretationSemantic proximity Read ↗

Identification and phenotype of MAIT cells in cattle and their response to bacterial infectionsSemantic proximity Read ↗

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cellsSemantic proximity Read ↗

Single cell transcriptional profiling reveals helper, effector, and regulatory MAIT cell populations enriched during homeostasis and activationSemantic proximity Read ↗

Unveiling the immunological landscape of disseminated tuberculosis: a single-cell transcriptome perspectiveSemantic proximity Read ↗

Antigen Recognition by MR1-Reactive T Cells; MAIT Cells, Metabolites, and Remaining Mysteries.Semantic proximity Read ↗

Diverse MR1-restricted T cells in mice and humansSemantic proximity Read ↗

Human Neonatal MR1T Cells Have Diverse TCR Usage, are Less Cytotoxic and are Unable to Respond to Many Common Childhood PathogensSemantic proximity Read ↗

Human Neonatal MR1T Cells Have Diverse TCR Usage, are Less Cytotoxic and are Unable to Respond to Many Common Childhood PathogensSemantic proximity Read ↗

Peptide Driven Identification of TCRs (PDI-TCR) reveals dynamics and phenotypes of CD4 T cells in tuberculosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.