Article

Rare non-coding variants are associated with plasma lipid traits in a founder population

2017-05-24

Abstract excerpt

Founder populations are ideally suited for studies on the clinical effects of alleles that are rare in general populations but occur at higher frequencies in these isolated populations. Whole genome sequencing in 98 South Dakota Hutterites, a founder population of European descent, and subsequent imputation to the Hutterite pedigree revealed 660,238 single nucleotide polymorphisms (SNPs; 98.9% non-coding) that are...

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Literature Corpus work: cc1243ee-765f-5b23-8865-93c54b6e506c
DOI: 10.1101/141960

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