Article

Whole genome sequence analysis of blood lipid levels in >66,000 individuals

2021-10-12

Abstract excerpt

Plasma lipids are heritable modifiable causal factors for coronary artery disease, the leading cause of death globally. Despite the well-described monogenic and polygenic bases of dyslipidemia, limitations remain in discovery of lipid-associated alleles using whole genome sequencing, partly due to limited sample sizes, ancestral diversity, and interpretation of potential clinical significance. Increasingly larger...

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Literature Corpus work: 52b68b49-0d1c-579d-b349-bbc15c5cb2ad
DOI: 10.1101/2021.10.11.463514

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