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Article

Rare non-coding variants are associated with plasma lipid traits in a founder population.

Scientific reports - 27 Nov 2017

Igartua Catherine, Mozaffari Sahar V, Nicolae Dan L, Ober Carole

Abstract excerpt

Founder populations are ideally suited for studies on the clinical effects of alleles that are rare in general populations but occur at higher frequencies in these isolated populations. Whole genome sequencing in 98 Hutterites, a founder population of European descent, and subsequent imputation revealed 660,238 single nucleotide polymorphisms that are rare (<1%) or absent in European populations, but occur at...

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Identifiers

PMID: 29180722
DOI: 10.1038/s41598-017-16550-8
PMCID: PMC5704019

Genes

APOC3
GOT2
LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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