Article

Exome wide association study for blood lipids in 1,158,017 individuals from diverse populations

2024-09-18

Abstract excerpt

Rare coding alleles play crucial roles in the molecular diagnosis of genetic diseases. However, the systemic identification of these alleles has been challenging due to their scarcity in the general population. Here, we discovered and characterized rare coding alleles contributing to genetic dyslipidemia, a principal risk for coronary artery disease, among over a million individuals combining three large contempor...

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Literature Corpus work: 175d7206-9d59-59ea-a2fa-676b2f93ca49
DOI: 10.1101/2024.09.17.24313718

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