Article

Single-cell, multi-region profiling of the macaque brain across the lifespan

2025-11-01

Abstract excerpt

Brain aging is a complex process with profound health and societal consequences. However, the molecular and cellular pathways that govern its temporal progression–along with any cell type-, region-, and sex-specific heterogeneity in such progression–remain poorly defined. Here, we present a transcriptomic atlas of 5.3 million cells from 582 samples spanning 11 brain regions of 55 rhesus macaques (29 female, 26 mal...

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Literature Corpus work: ca5e7040-9c9f-545b-b424-ca5b52b2bbd4
DOI: 10.1101/2025.10.31.685880

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