Article

Single-Cell Transcriptomic Insights into Conserved and Divergent Oligodendrocyte Lineage Programs Across Species

2025-11-14

Abstract excerpt

<title>Abstract</title> <p>Oligodendrocyte lineage cells (OLLCs) are essential for myelination and neural support, yet how their transcriptional programs are conserved or diverge across species remains unclear. We analyzed around one million hippocampal single-cell and single-nucleus transcriptomes from humans, cynomolgus macaques, rhesus macaques, and mice. OLLCs exhibited high transcriptional conservation, with...

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Literature Corpus work: c29be1e3-1643-5ea7-84e2-e9f95be36a79
DOI: 10.21203/rs.3.rs-7827530/v1

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