Article
A global view of aging and Alzheimer’s pathogenesis-associated cell population dynamics and molecular signatures in the human and mouse brains
2022-09-30
Abstract excerpt
<h4>Summary</h4> Conventional single-cell genomics approaches are limited by throughput and thus may have failed to capture aspects of the molecular signatures and dynamics of rare cell types associated with aging and diseases. Here, we developed EasySci , an extensively improved single-cell combinatorial indexing strategy, for investigating the age-dependent dynamics of transcription and chromatin accessibility...
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Identifiers and source
- Literature Corpus work
- d68845d6-ec83-5918-83d9-a464a2c6c884
- DOI
- 10.1101/2022.09.28.509825