Article

Cell type-specific associations with Alzheimer’s Disease conserved across racial and ethnic groups

2025-04-15

Abstract excerpt

Genomic studies at single-cell resolution have implicated multiple cell types associated with clinical and pathological traits in Alzheimer’s Disease (AD), but have not examined common features across broad, multi-ethnic populations, and across multiple regions. To bridge this gap, we performed single-nucleus RNA-seq and ATAC-seq profiling of cortical and subcortical brain regions from post-mortem samples across N...

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Literature Corpus work: bcf27a0d-1682-589c-b2e6-f671350803e6
DOI: 10.1101/2025.04.14.648597

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