Article

Multimodal brain cell atlas across the adult macaque lifespan

2025-03-12

Abstract excerpt

<h4>SUMMARY</h4> High-throughput single-cell omics of non-human primate tissues present a remarkable opportunity to study primate brain aging. Here, we introduce a transcriptomic and chromatin accessibility landscape of 1,985,317 cells from eight brain regions of 13 cynomolgus female monkeys spanning adult lifespan including exceptionally old individuals up to 29-years old. This dataset uncovers dynamic molecular...

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Literature Corpus work: d5b9f733-bdd9-5987-b915-ef0d4dccecdb
DOI: 10.1101/2025.03.11.641786

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