Article

A systematic analysis of human transmembrane E3-RING proteins

2011-01-01

Abstract excerpt

The reversible covalent conjugation of the small highly conserved ubiquitin protein modifier to selective substrates plays central roles in countless proteolytic and non-proteolytic cellular functions. Substrate protein ubiquitination is co-ordinated by the sequential activity of three distinct classes of proteins: (i) E1-activating enzymes, (ii) E2-conjugating enzymes, and (iii) E3-protein ligases. Really Interes...

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Literature Corpus work: c9c1480d-fd51-5abd-8637-30a6c9c7de58
DOI: 10.17638/00005913

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