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Article

RING E3-Catalyzed E2 Self-Ubiquitination Attenuates the Activity of Ube2E Ubiquitin-Conjugating Enzymes.

Journal of molecular biology - 3 Jul 2015

Banka Prerana Agarwal, Behera Adaitya Prasad, Sarkar Sayani, Datta Ajit B

Abstract excerpt

Ubiquitination of a target protein is accomplished through sequential actions of the E1, E2s, and the E3s. E2s dictate the modification topology while E3 ligases confer substrate specificity and recruit the cognate E2. Human genome codes for ~35 different E2 proteins; all of which contain the cha...

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Source

Identifiers

PMID: 25960396
DOI: 10.1016/j.jmb.2015.04.011

Genes

UBC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25960396-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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