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Role of MARCH E3 ubiquitin ligases in cancer development

22 Jul 2024

Abstract excerpt

Membrane-associated RING-CH (MARCH) E3 ubiquitin ligases, a family of RING-type E3 ubiquitin ligases, have garnered increased attention for their indispensable roles in immune regulation, inflammation, mitochondrial dynamics, and lipid metabolism. The MARCH E3 ligase family consists of eleven distinct members, and the dysregulation of many of these members has been documented in several human malignancies. Over...

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PMID: 39037545
DOI: 10.1007/s10555-024-10201-x

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