Article

Enhancing Virus-Specific T Cell Persistence: L-Arginine Supplementation Improves the Durability of CD8 + T Cells for Immunotherapy

2025-10-03

Abstract excerpt

<title>Abstract</title> Virus-specific T cell (VST) therapy offers a promising treatment for life-threatening viral infections following allogeneic hematopoietic stem cell transplantation (HSCT). However, the efficacy of VST therapy remains limited by apoptosis, exhaustion, and loss of stem-like properties with advancing differentiation. In this study, we demonstrate that supplementation of basic culture med...

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Literature Corpus work: c8f3e8b3-d5e4-5218-ac2c-ff07acf35f77
DOI: 10.21203/rs.3.rs-7518621/v1

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