Aging Of Antiviral CD8 ⁺ Memory T Cells Fosters Increased Survival, Metabolic Adaptations And Lymphoid Tissue Homing

Abstract excerpt

<h4>ABSTRACT</h4> Aging of established antiviral T cell memory fosters a series of progressive adaptations that paradoxically improve rather than compromise protective CD8 + T cell immunity. We now provide evidence that this gradual evolution, the pace of which is contingent on the precise context of the primary response, also impinges on the molecular mechanisms that regulate CD8 + memory T cell (CD8 + T M )...

Topics

Open a Topic to create a Post that cites this publication.

• CAR-T cell therapy research
• CD8-Positive T-Lymphocytes
• Cytomegalovirus and herpesvirus research
• Immune Cell Function and Interaction
• Immunologic Memory
• Phenotype
• Stem Cells
• T-cell and B-cell Immunology

Identifiers and source

Literature Corpus work

bf70818b-0084-5d10-928e-382919b320fa

DOI

10.1101/191932