Article

A molecular census of midbrain dopaminergic neurons in Parkinson’s disease

2021-06-16

Abstract excerpt

Midbrain dopamine (DA) neurons in the substantia nigra pars compacta (SNpc) project widely throughout the central nervous system, playing critical roles in voluntary movements, reward processing, and working memory. Many of these neurons are highly sensitive to neurodegeneration in Parkinson’s Disease (PD), and their loss correlates strongly with the pathognomonic symptoms. To characterize these populations molecu...

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Literature Corpus work: c8ea8bb7-010f-5284-a646-58c02ec01b92
DOI: 10.1101/2021.06.16.448661

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