Article
Dopamine across timescales and cell types: Relevance for phenotypes in Parkinson's disease progression.
Experimental neurology - 1 Apr 2024
Seiler Jillian L, Zhuang Xiaowen, Nelson Alexandra B, Lerner Talia N
Abstract excerpt
Dopamine neurons in the substantia nigra pars compacta (SNc) synthesize and release dopamine, a critical neurotransmitter for movement and learning. SNc dopamine neurons degenerate in Parkinson's Disease (PD), causing a host of motor and non-motor symptoms. Here, we review recent conceptual advances in our basic understanding of the dopamine system - including our rapidly advancing knowledge of dopamine neuron...
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