Article

USP1 activates the Wnt/β-catenin pathway by deubiquitinating KRT17, thereby facilitating thyroid cancer proliferation

2024-03-22

Abstract excerpt

Post-translational modification through ubiquitination is widely acknowledged for its pivotal regulatory role in tumor onset and progression. Ubiquitin ligases and deubiquitinases can modulate tumor advancement by impacting the expression of key proteins. Nonetheless, the precise contribution of ubiquitination and deubiquitinases in the onset of thyroid cancer (TC) remains to be comprehensively understood. Initial...

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Literature Corpus work: c8e6120a-adb1-57f6-9e3e-f5aa0a462329
DOI: 10.21203/rs.3.rs-4092791/v1

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