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An Overview of the Deubiquitinase USP53: A Promising Diagnostic Marker and Therapeutic Target.

Current protein & peptide science - 1 Jan 2024

Xia Guangce, Guo Yulin, Zhang Jiajia, Han Meng, Meng Xiangchao, Lv Ji

Abstract excerpt

Ubiquitination and deubiquitination are important mechanisms to maintain normal physiological activities, and their disorders or imbalances can lead to various diseases. As a subgroup of deubiquitinases (DUBs), the ubiquitin-specific peptidase (USP) family is closely related to many biological processes. USP53, one of the family members, is widely expressed in human tissues and participates in a variety of life...

Topics

Humans
Neoplasms
Animals
Biomarkers, Tumor
Ubiquitin-Specific Proteases
Molecular Targeted Therapy
Ubiquitination
Mutation
Cholestasis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39300775
DOI: 10.2174/0113892037292440240518194922
PMCID: PMC11348463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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