Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Over-Expression of Deubiquitinating Enzyme USP14 in Lung Adenocarcinoma Promotes Proliferation through the Accumulation of β-Catenin

23 May 2013

Abstract excerpt

The deubiquitinating enzyme USP14 has been identified and biochemically studied, but its role in lung cancer remains to be elucidated. The aim of this study was to evaluate the prognostic significance of USP14 in patients with lung adenocarcinoma and to define its role in lung cancer cell proliferation. USP14 mRNA levels in different non-small cell lung cancer (NSCLC) cell lines were detected by real-time qPCR....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to RNA modifications and cancer
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23702845
DOI: 10.3390/ijms140610749

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Over-Expression of Deubiquitinating Enzyme USP14 in Lung Adenocarcinoma Promotes Proliferation through the Accumulation of β-CateninPMID 23702845Read ↗

USP14 Inhibition Regulates Tumorigenesis by Inducing Autophagy in Lung Cancer In VitroSemantic proximity Read ↗

USP4 expression independently predicts favorable survival in lung adenocarcinomaSemantic proximity Read ↗

Deubiquitinase USP5 promotes non-small cell lung cancer cell proliferation by stabilizing cyclin D1Semantic proximity Read ↗

Targeting deubiquitinase USP28 for cancer therapySemantic proximity Read ↗

Ubiquitin-specific protease 8 is a novel prognostic marker in early-stage lung adenocarcinoma.Semantic proximity Read ↗

Transcription factor AP2 enhances malignancy of non-small cell lung cancer through upregulation of USP22 gene expressionSemantic proximity Read ↗

Expression patterns of USP22 and potential targets BMI-1, PTEN, p-AKT in non-small-cell lung cancer.Semantic proximity Read ↗

Cellular functions, molecular signalings and therapeutic applications: Translational potential of deubiquitylating enzyme USP9X as a drug target in cancer treatmentSemantic proximity Read ↗

USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy.Semantic proximity Read ↗

USP7 deubiquitinates KRAS and promotes non-small cell lung cancer.Semantic proximity Read ↗

USP14 Regulates DNA Damage Response and Is a Target for Radiosensitization in Non-Small Cell Lung CancerSemantic proximity Read ↗

USP28 deletion and small molecule inhibition destabilises c-Myc and elicits regression of squamous cell lung carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.