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Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma

22 Jul 2024

Abstract excerpt

Papillary thyroid carcinoma (PTC) is the most prevalent malignancy of the thyroid. Fibroblast growth factor receptor 1 (FGFR1) is highly expressed in PTC and works as an oncogenic protein in this disease. In this report, we wanted to uncover a new mechanism that drives overexpression of FGFR1 in PTC. Analysis of FGFR1 expression in clinical specimens and PTC cells revealed that FGFR1 expression was enhanced in...

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PMID: 39037153
DOI: 10.4081/ejh.2024.4048

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