Article

Scywalker: scalable end-to-end data analysis workflow for nanopore single-cell transcriptome sequencing

2024-02-24

Abstract excerpt

We introduce scywalker , an innovative and scalable package developed to comprehensively analyze long-read nanopore sequencing data of full-length single-cell or single-nuclei cDNA. Existing nanopore single-cell data analysis tools showed severe limitations in handling current data sizes. We developed novel scalable methods for cell barcode demultiplexing and single-cell isoform calling and quantification and inc...

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Literature Corpus work: 0e08fad3-4413-546e-8b5f-43ca2b71d628
DOI: 10.1101/2024.02.22.581508

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