Article

scCAT-seq:single-cell identification and quantification of mRNA isoforms by cost-effective short-read sequencing of cap and tail

2019-12-12

Abstract excerpt

The differences in transcription start sites (TSS) and transcription end sites (TES) among gene isoforms can affect the stability, localization, and translation efficiency of mRNA. Isoforms also allow a single gene different functions across various tissues and cells However, methods for efficient genome-wide identification and quantification of RNA isoforms in single cells are still lacking. Here, we introduce si...

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Literature Corpus work: c9b88331-bf0b-5a4a-bfed-b860ef42dc4e
DOI: 10.1101/2019.12.11.873505

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