Article

Single-cell RNA counting at allele- and isoform-resolution using Smart-seq3

2019-10-25

Abstract excerpt

Large-scale sequencing of RNAs from individual cells can reveal patterns of gene, isoform and allelic expression across cell types and states 1 . However, current single-cell RNA-sequencing (scRNA-seq) methods have limited ability to count RNAs at allele- and isoform resolution, and long-read sequencing techniques lack the depth required for large-scale applications across cells 2,3 . Here, we introduce Smart-se...

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Literature Corpus work: d8ddaab1-1a78-52e5-beb6-2920a44ac237
DOI: 10.1101/817924

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