Article

Chromatin state transition underlies the temporal changes in gene expression during cardiomyocyte maturation

2021-12-28

Abstract excerpt

Congenital heart disease (CHD) is often rooted in gene expression anomalies that occur during heart development. As cells commit to a specific lineage, chromatin dynamics and developmental plasticity generally become more limited. However, it remains unclear how differentiated cardiomyocytes (CMs) undergo morphological and functional adaptations to the postnatal environment during their maturation. In this work, w...

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Literature Corpus work: c831d208-27bb-51b1-a3d0-3dcfbf38a6f9
DOI: 10.1101/2021.12.28.474318

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