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Article

Epigenetic and lncRNA regulation of cardiac pathophysiology.

Biochimica et biophysica acta - 1 Jul 2016

Chang Ching-Pin, Han Pei

Abstract excerpt

Our developmental studies provide an insight into the pathogenesis of heart failure in adults. These studies reveal a mechanistic link between fetal cardiomyocytes and pathologically stressed adult cardiomyocytes at the level of chromatin regulation. In embryos, chromatin-regulating factors within the cardiomyocytes respond to developmental signals to program cardiac gene expression to promote cell proliferation...

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Topics

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Share to Chromatin Assembly and Disassembly
Share to DNA Helicases
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene-Environment Interaction

Share to Heart Diseases

Share to Myocytes, Cardiac

Share to Nuclear Proteins

Share to RNA, Long Noncoding

Source

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Identifiers

PMID: 26969820
DOI: 10.1016/j.bbamcr.2016.03.005
PMCID: PMC7393981

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