Article

Protective targets of PfSPZ vaccines identified from whole-genome sieve analysis of isolates from malaria vaccine efficacy trials in West Africa

2025-03-06

Abstract excerpt

<h4>Summary</h4> Identification of antigens targeted by a protective response is a central quest in malaria vaccinology. Whole-genome sieve analysis (SA WG ) in samples collected from placebo-controlled field trials of Plasmodium falciparum (Pf) sporozoite (SPZ) vaccines may enable identification of Pf pre-erythrocytic antigens. We applied SA WG to genomic data generated from Pf isolates collected during two field...

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Literature Corpus work: c7da5d59-e274-551d-82a9-68367584f88f
DOI: 10.1101/2025.03.04.25323352

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