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Article

Genome-wide variation and identification of vaccine targets in the Plasmodium falciparum genome.

Nature genetics - 1 Jan 2007

Mu Jianbing, Awadalla Philip, Duan Junhui, McGee Kate M, Keebler Jon, Seydel Karl, McVean Gilean A T, Su Xin-zhuan

Abstract excerpt

One goal in sequencing the Plasmodium falciparum genome, the agent of the most lethal form of malaria, is to discover vaccine and drug targets. However, identifying those targets in a genome in which approximately 60% of genes have unknown functions is an enormous challenge. Because the majority of known malaria antigens and drug-resistant genes are highly polymorphic and under various selective pressures,...

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Identifiers

PMID: 17159981
DOI: 10.1038/ng1924

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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