Article

Diversity and selection analyses identify transmission-blocking antigens as the optimal vaccine candidates in<i>Plasmodium falciparum</i>

2024-05-12

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> A highly effective vaccine for malaria remains an elusive target, at least in part due to the under-appreciated natural parasite variation. This study aimed to investigate genetic and structural variation, and immune selection of leading malaria vaccine candidates across the Plasmodium falciparum ’s life cycle. <h4>Methods</h4> We analyzed 325 P. falciparum whole genome sequenc...

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Literature Corpus work: bb08f797-2191-5cfd-9c33-19786a312dae
DOI: 10.1101/2024.05.11.24307175

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