Article

Optimization of whole-genome sequencing of Plasmodium falciparum from low-density dried blood spot samples

2021-02-11

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Whole-genome sequencing (WGS) is becoming increasingly useful to study the biology, epidemiology, and ecology of malaria parasites. Despite ease of sampling, DNA extracted from dried blood spots (DBS) has a high ratio of human DNA compared to parasite DNA, which poses a challenge for downstream genetic analyses. The effects of multiple methods for DNA extraction,...

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Literature Corpus work: 56e1de24-af11-5d84-914a-adba5fe5159e
DOI: 10.21203/rs.3.rs-69257/v4

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