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Whole-genome analysis of Malawian <i>Plasmodium falciparum</i> isolates identifies potential targets of allele-specific immunity to clinical malaria

2020-09-18

Abstract excerpt

Individuals acquire immunity to clinical malaria after repeated Plasmodium falciparum infections. This immunity to disease is thought to reflect the acquisition of a repertoire of responses to multiple alleles in diverse parasite antigens. In previous studies, we identified polymorphic sites within individual antigens that are associated with parasite immune evasion by examining antigen allele dynamics in individu...

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Literature Corpus work
0d74dec5-f262-5d54-b5e7-b3597bc2e704
DOI
10.1101/2020.09.16.20196253
Open publication

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Whole-genome analysis of Malawian <i>Plasmodium falciparum</i> isolates identifies potential targets of allele-specific immunity to clinical malariaDOI 10.1101/2020.09.16.20196253
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