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Whole-genome surveillance identifies markers of Plasmodium falciparum drug resistance and novel genomic regions under selection in Mozambique

26 Sept 2023

Abstract excerpt

ABSTRACT The emergence of Plasmodium falciparum drug resistance threatens the efficacy of antimalarial therapies globally. Population genomic studies have been instrumental in mapping malaria genes associated with drug resistance. However, to understand the impact of regional malaria control strategies on the malaria genome, it is necessary to examine parasite subpopulations at the country level. Here, we use...

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PMID: 37750720
DOI: 10.1128/mbio.01768-23

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