Article

A cell-free strategy for profiling intracellular antibiotic sensitivity and resistance

2023-04-13

Abstract excerpt

Antimicrobial resistance (AMR) is a pandemic spread across multiple priority infectious disease threats. While the cell envelope plays a key role in AMR, this also makes it challenging to study how antibiotics function inside the cell. Herein, we present a Klebsiella pneumoniae cell-free gene expression (CFE) platform for the rapid profiling of intracellular antibiotic sensitivity and resistance. This cell-free a...

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Literature Corpus work: c78ae84a-9a70-52f2-8763-cdf8dce70a82
DOI: 10.1101/2023.04.13.536698

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