Article

A cell-free strategy for profiling of intracellular antibiotic sensitivity and resistance

2023-05-23

Abstract excerpt

Antimicrobial resistance (AMR) is a pandemic spread across multiple priority infectious disease threats. Herein, we present a Klebsiella pneumoniae cell-free gene expression (CFE) system for the rapid profiling of intracellular antibiotic sensitivity and resistance. Specifically, this cell-free approach provides multiple antibiotic targets, which we exploit to identify which antibiotics are potent inside the cell...

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Literature Corpus work: 78f4b5e0-14c4-5f49-87c8-243bda79a3f3
DOI: 10.21203/rs.3.rs-2923903/v1

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