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Article

A metatranscriptome based approach to predict multidrug resistance phenotypes in Klebsiella pneumoniae without culturing.

Journal of global antimicrobial resistance - 1 Jun 2026

Xiang Zhoufu, Guan Jiaojiao, Wang Han, Wu Wanhua, Chen Sijun, Wang Siqi, Jiang Zihao, Hu Yiyi, Xiang Miao, Huang Tingsheng, Tian Hongpan, Sun Yanni, Li Yirong, Hou Wei, Chen Liangjun

Abstract excerpt

INTRODUCTION: Antimicrobial resistance (AMR), particularly multidrug resistance (MDR) in Klebsiella pneumoniae, has emerged as a significant global public health challenge. However, accurate resistance phenotype prediction remains difficult. METHODS: Metatranscriptomic analysis was performed on bronchoalveolar lavage fluid from 31 patients. After removing host and rRNA sequences, antimicrobial resistance genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41997420
DOI: 10.1016/j.jgar.2026.04.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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