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Genome-scale metabolic modeling reveals increased reliance on valine catabolism in clinical isolates of Klebsiella pneumoniae

2021-09-09

Abstract excerpt

Infections due to carbapenem-resistant Enterobacteriaceae have recently emerged as one of the most urgent threats to hospitalized patients within the United States and Europe. By far the most common etiological agent of these infections is Klebsiella pneumoniae , frequently manifesting in hospital-acquired pneumonia with a mortality rate of ∼50% even with antimicrobial intervention. We performed transcriptomic an...

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Literature Corpus work: 0f32f26d-0dc6-5bdf-9490-ec9fc400773f
DOI: 10.1101/2021.09.08.459555

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Genome-scale metabolic modeling reveals increased reliance on valine catabolism in clinical isolates of <i>Klebsiella pneumoniae</i>

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