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A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance

7 Jun 2022

Abstract excerpt

Detailed knowledge on how bacteria evade antibiotics and eventually develop resistance could open avenues for novel therapeutics and diagnostics. It is thereby key to develop a comprehensive genome-wide understanding of how bacteria process antibiotic stress, and how modulation of the involved processes affects their ability to overcome said stress. Here we undertake a comprehensive genetic analysis of how the...

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PMID: 35672367
DOI: 10.1038/s41467-022-30967-4

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