Article

High-Resolution Detection of Hidden Antibiotic Resistance with the Dilution-and-Delay (DnD) Susceptibility Assay

2025-08-11

Abstract excerpt

Rising rates of antibiotic treatment failure highlight the complexity of resistance mechanisms. While conventional, genetically encoded resistance is well established, recent studies have uncovered widespread non-canonical mechanisms driven by phenotypically insensitive subpopulations hiding in seemingly susceptible populations, such as heteroresistance, persistence or adaptive resistance. These variants are not o...

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Literature Corpus work: 21d21ad0-5998-5a2c-841e-eb0757578320
DOI: 10.1101/2025.08.11.669743

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