Article

Glycolysis Inhibition Regulates Endothelial Junctions by Perturbing Actin and Focal Adhesions

2020-10-22

Abstract excerpt

One of the central functions of the endothelium is to maintain a vascular barrier that prevents fluid leakiness and immune cell influx from the circulating blood into the tissue. The barrier integrity of the endothelium is largely controlled by adherens junctions (AJs) and the key AJ molecule VE-cadherin, which maintains cell cohesion via homotypic trans-interaction with VE-cadherin molecules on neighboring endoth...

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Literature Corpus work: c785ebe9-8599-5480-be6b-a0b52eb653a2
DOI: 10.1101/2020.10.22.351148

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