Modulating endothelial barrier function by targeting vimentin phosphorylation.

Abstract excerpt

Vimentin is a major intermediate filament protein in vascular endothelial cells which might be involved in their function as a barrier tissue. It is proposed to dynamically maintain integrity of the endothelium as a tightly regulated permeability barrier that is subjected to a variety of shear and contractile forces. The results described in this report demonstrate that vimentin plays that role through mechanisms...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Capillary Permeability
• Share to Drug Resistance