Article
F-actin-anchored focal adhesions distinguish endothelial phenotypes of human arteries and veins.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2014
van Geemen Daphne, Smeets Michel W J, van Stalborch Anne-Marieke D, Woerdeman Leonie A E, Daemen Mat J A P, Hordijk Peter L, Huveneers Stephan
Abstract excerpt
OBJECTIVE: Vascular endothelial-cadherin- and integrin-based cell adhesions are crucial for endothelial barrier function. Formation and disassembly of these adhesions controls endothelial remodeling during vascular repair, angiogenesis, and inflammation. In vitro studies indicate that vascular cytokines control adhesion through regulation of the actin cytoskeleton, but it remains unknown whether such regulation...
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